Abstract
A smart drug delivery system with cancer cell targeting and bioresponsive controlled drug release has been constructed by taking advantage of a protein-capped mesoporous nanovalve and a DNA aptamer.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Aptamers, Nucleotide / chemistry*
-
Avidin / chemistry
-
Avidin / metabolism
-
Biotin / chemistry
-
Biotin / metabolism
-
Cell Line, Tumor
-
Cell Survival / drug effects
-
Doxorubicin / chemistry
-
Doxorubicin / toxicity
-
Drug Carriers / chemistry*
-
Humans
-
Nanoparticles / chemistry*
-
Porosity
-
Silicon Dioxide / chemistry
-
Vitamins / chemistry
-
Vitamins / metabolism
Substances
-
Aptamers, Nucleotide
-
Drug Carriers
-
Vitamins
-
Avidin
-
Biotin
-
Silicon Dioxide
-
Doxorubicin