Efficacy of combined antiviral therapy with lamivudine and tenofovir in a liver transplanted girl with de novo hepatitis B virus infection

M Tufano; D Liccardo; S Riva; M Candusso; G Torre; R Iorio

doi:10.1111/tid.12057

Efficacy of combined antiviral therapy with lamivudine and tenofovir in a liver transplanted girl with de novo hepatitis B virus infection

Transpl Infect Dis. 2013 Apr;15(2):E81-4. doi: 10.1111/tid.12057. Epub 2013 Feb 6.

Authors

M Tufano¹, D Liccardo, S Riva, M Candusso, G Torre, R Iorio

Affiliation

¹ Department of Pediatric Hepatology, University of Naples, Federico II, Naples, Italy.

PMID: 23387823
DOI: 10.1111/tid.12057

Abstract

The management of de novo hepatitis B (HBV) infection in children after liver transplantation is not well defined. Because this infection may induce severe liver disease in the graft liver, an efficient antiviral therapy is desirable. Here, we describe the favorable viral outcome observed in a liver transplanted girl with de novo HBV infection following combination therapy with lamivudine and tenofovir.

Publication types

Case Reports

MeSH terms

Adenine / analogs & derivatives*
Adenine / therapeutic use
Antiviral Agents / therapeutic use*
Child, Preschool
Drug Therapy, Combination
Female
Hepatitis B / drug therapy*
Hepatitis B virus / isolation & purification
Humans
Lamivudine / therapeutic use*
Liver Transplantation*
Organophosphonates / therapeutic use*
Tenofovir
Treatment Outcome

Substances

Antiviral Agents
Organophosphonates
Lamivudine
Tenofovir
Adenine