[Review in geriatric medicine 2012]

Rev Med Suisse. 2013 Jan 9;9(368):40-3.
[Article in French]

Abstract

2012 brought additional evidence regarding the benefits of exercise in older persons in showing morbidity compression in those most active. Several studies invite to revise therapeutic targets in older diabetics, especially those with cognitive impairment or dementia where a value of 8 to 9% for HbAlc might be a good compromise. On the dementia side, a study suggests that biological and structural abnormalities associated with Alzheimer's disease might occur as early as 25 years before its first clinical manifestations. On the therapeutic side, ginkgo and the double therapy with memantine and donepezil did not make it in RCTs, and two studies about treatments for behavioral symptoms of dementia showed that interruption could be deleterious.

Publication types

  • Review

MeSH terms

  • Aged
  • Dementia / epidemiology
  • Dementia / etiology
  • Dementia / prevention & control
  • Dementia / therapy
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / therapy
  • Geriatrics / methods
  • Geriatrics / trends*
  • Glycated Hemoglobin / metabolism
  • Humans
  • Motor Activity / physiology
  • Time Factors

Substances

  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human