[Myelotoxicity due to interaction between azathioprine and allopurinol in a patient with Crohn's disease]

Gastroenterol Hepatol. 2013 Apr;36(4):298-9. doi: 10.1016/j.gastrohep.2012.10.002. Epub 2012 Dec 28.
[Article in Spanish]
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Allopurinol / adverse effects*
  • Allopurinol / pharmacology
  • Allopurinol / therapeutic use
  • Azathioprine / adverse effects*
  • Azathioprine / pharmacokinetics
  • Azathioprine / therapeutic use
  • Biotransformation / drug effects
  • Bone Marrow Diseases / chemically induced*
  • Crohn Disease / drug therapy*
  • Drug Interactions
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Immunosuppressive Agents / pharmacology
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Mercaptopurine / metabolism
  • Mercaptopurine / pharmacokinetics
  • Methyltransferases / antagonists & inhibitors
  • Methyltransferases / physiology
  • Xanthine Oxidase / antagonists & inhibitors
  • Xanthine Oxidase / physiology

Substances

  • Immunosuppressive Agents
  • Allopurinol
  • Mercaptopurine
  • Xanthine Oxidase
  • Methyltransferases
  • thiopurine methyltransferase
  • Azathioprine