A CN- specific turn-on phosphorescent probe with probable application for enzymatic assay and as an imaging reagent

Chem Commun (Camb). 2013 Jan 11;49(3):255-7. doi: 10.1039/c2cc37243f. Epub 2012 Nov 21.

Abstract

A new "turn-on" luminescence probe for imaging the uptake of 0.2 ppm inorganic CN(-) in live HeLa cells as well as for probing the CN(-) generation through an enzymatic process in a virtual aqueous medium at appropriate pH.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Copper / chemistry
  • Cyanides / chemistry*
  • Enzyme Assays
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Hydrogen-Ion Concentration
  • Microscopy, Confocal
  • Water / chemistry

Substances

  • Cyanides
  • Fluorescent Dyes
  • Water
  • Copper