BRAF mutations in colorectal cancer: clinical relevance and role in targeted therapy

J Natl Compr Canc Netw. 2012 Nov 1;10(11):1456-8. doi: 10.6004/jnccn.2012.0148.
No abstract available

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use
  • Biomarkers, Tumor / genetics*
  • Colorectal Neoplasms / diagnosis
  • Colorectal Neoplasms / drug therapy
  • Colorectal Neoplasms / genetics*
  • Drug Resistance, Neoplasm
  • Humans
  • Molecular Targeted Therapy*
  • Mutation, Missense
  • Prognosis
  • Proto-Oncogene Proteins B-raf / genetics*

Substances

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf