Virulence factors of Toxoplasma gondii

Microbes Infect. 2012 Dec;14(15):1403-10. doi: 10.1016/j.micinf.2012.09.005. Epub 2012 Sep 21.

Abstract

Toxoplasma gondii virulence is dependent on factors involved in either parasite-host cell interaction, or in host immune response. It is essentially defined in the mouse and little is known concerning human infection. The genetic dependence of virulence is a growing field, benefiting from the recent development of research of the population structure of T. gondii.

Publication types

  • Review

MeSH terms

  • Animals
  • Host-Parasite Interactions
  • Humans
  • Mice
  • Toxoplasma / metabolism
  • Toxoplasma / pathogenicity*
  • Toxoplasmosis / parasitology
  • Virulence Factors / metabolism
  • Virulence Factors / physiology*

Substances

  • Virulence Factors