Varicella zoster central nervous system vasculitis after allogeneic hematopoietic stem cell transplant successfully treated with cyclophosphamide

B Molina; M Gonzalez-Vicent; G Albi; M Andión; B Herrero; J Sevilla; M A Díaz

doi:10.1111/j.1399-3062.2012.00783.x

Varicella zoster central nervous system vasculitis after allogeneic hematopoietic stem cell transplant successfully treated with cyclophosphamide

Transpl Infect Dis. 2012 Oct;14(5):E107-10. doi: 10.1111/j.1399-3062.2012.00783.x. Epub 2012 Sep 11.

Authors

B Molina¹, M Gonzalez-Vicent, G Albi, M Andión, B Herrero, J Sevilla, M A Díaz

Affiliation

¹ Stem Cell Transplant Unit, Hospital Niño Jesus, Madrid, Spain.

PMID: 22967359
DOI: 10.1111/j.1399-3062.2012.00783.x

Abstract

We report the first case of varicella zoster central nervous system vasculitis, to our knowledge, which responded to intravenous pulses of cyclophosphamide in an immunocompromised child with severe and progressive disease, without sequelae.

Publication types

Case Reports

MeSH terms

Child
Cyclophosphamide / administration & dosage
Cyclophosphamide / therapeutic use*
Hematopoietic Stem Cell Transplantation / adverse effects*
Herpes Zoster / drug therapy*
Herpes Zoster / virology
Humans
Immunosuppressive Agents / administration & dosage
Immunosuppressive Agents / therapeutic use*
Male
Transplantation, Homologous / adverse effects
Treatment Outcome
Vasculitis, Central Nervous System / drug therapy*
Vasculitis, Central Nervous System / virology

Substances

Immunosuppressive Agents
Cyclophosphamide