Intakes and sources of isoflavones, lignans, enterolignans, coumestrol and soya-containing foods in the Norfolk arm of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk), from 7 d food diaries, using a newly updated database

Public Health Nutr. 2013 Aug;16(8):1454-62. doi: 10.1017/S1368980012003904. Epub 2012 Sep 3.

Abstract

Objective: A diet rich in phyto-oestrogens has been suggested to protect against a variety of common diseases but UK intake data on phyto-oestrogens or their food sources are sparse. The present study estimates the average intakes of isoflavones, lignans, enterolignans and coumestrol from 7 d food diaries and provides data on total isoflavone, lignan and phyto-oestrogen consumption by food group.

Design: Development of a food composition database for twelve phyto-oestrogens and analysis of soya food and phyto-oestrogen consumption in a populationbased study.

Setting: Men and women, aged 40–79 years, from the general population participating in the Norfolk arm of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) between 1993 and 1997, with nutrient and food data from 7 d food diaries.

Subjects: A subset of 20 437 participants.

Results: The median daily phyto-oestrogen intake for all men was 1199 mg (interquartile range 934–1537mg; mean 1504mg, SD 1502mg) and 888mg for all women (interquartile range 710–1135 mg; mean 1205 mg, SD 1701mg). In soya consumers, median daily intakes were higher: 2861 mg in men (interquartile range 1304–7269mg; mean 5051mg, SD 5031mg) and 3142 mg in women (interquartile range 1089–7327mg; mean 5396 mg, SD 6092 mg). In both men and women, bread made the greatest contribution to phyto-oestrogen intake – 40?8% and 35?6%, respectively. In soya consumers, vegetable dishes and soya/goat’s/sheep’s milks were the main contributors – 45?7% and 21?3% in men and 38?4% and 33?7% in women, respectively.

Conclusions: The ability to estimate phyto-oestrogen intake in Western populations more accurately will aid investigations into their suggested effects on health.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Animals
  • Coumestrol / administration & dosage*
  • Databases, Factual*
  • Diet
  • Diet Records*
  • Feeding Behavior*
  • Female
  • Goats
  • Humans
  • Isoflavones / administration & dosage*
  • Lignans / administration & dosage*
  • Linear Models
  • Male
  • Middle Aged
  • Milk
  • Nutritional Status
  • Phytoestrogens / administration & dosage
  • Prospective Studies
  • Sheep
  • Soy Foods
  • Vegetables

Substances

  • Isoflavones
  • Lignans
  • Phytoestrogens
  • Coumestrol