Trisomy 12 CLLs progress through NOTCH1 mutations

Leukemia. 2013 Mar;27(3):740-3. doi: 10.1038/leu.2012.239. Epub 2012 Aug 20.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosomes, Human, Pair 12 / genetics*
  • Disease Progression
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / pathology
  • Mutation / genetics*
  • Prognosis
  • RNA, Messenger / genetics
  • Real-Time Polymerase Chain Reaction
  • Receptor, Notch1 / genetics*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Trisomy / genetics*

Substances

  • NOTCH1 protein, human
  • RNA, Messenger
  • Receptor, Notch1