Feasibility and potential effectiveness of a non-pharmacological multidisciplinary care programme for persons with generalised osteoarthritis: a randomised, multiple-baseline single-case study

BMJ Open. 2012 Jul 19;2(4):e001161. doi: 10.1136/bmjopen-2012-001161. Print 2012.

Abstract

Objectives: To evaluate the feasibility and potential effectiveness of a 12-week, non-pharmacological multidisciplinary intervention in patients with generalised osteoarthritis (GOA).

Design: A randomised, concurrent, multiple-baseline single-case design. During the baseline period, the intervention period and the postintervention period, all participants completed several health outcomes twice a week on Visual Analogue Scales.

Setting: Rheumatology outpatient department of a specialised hospital in the Netherlands.

Participants: 1 man and four women (aged 51-76 years) diagnosed with GOA.

Primary outcome measures: To assess feasibility, the authors assessed the number of dropouts and adverse events, adherence rates and patients' satisfaction.

Secondary outcome measures: To assess the potential effectiveness, the authors assessed pain and self-efficacy using visual data inspection and randomisation tests.

Results: The intervention was feasible in terms of adverse events (none) and adherence rate but not in terms of participants' satisfaction with the intervention. Visual inspection of the data and randomisation testing demonstrated no effects on pain (p=0.93) or self-efficacy (p=0.85).

Conclusions: The results of the present study indicate that the proposed intervention for patients with GOA was insufficiently feasible and effective. The data obtained through this multiple-baseline study have highlighted several areas in which the therapy programme can be optimised.