Medulloblastoma/Primitive neuroectodermal tumor and germ cell tumors: the uncommon but potentially curable primary brain tumors

Ayman Samkari; Eugene Hwang; Roger J Packer

doi:10.1016/j.hoc.2012.04.002

Medulloblastoma/Primitive neuroectodermal tumor and germ cell tumors: the uncommon but potentially curable primary brain tumors

Hematol Oncol Clin North Am. 2012 Aug;26(4):881-95. doi: 10.1016/j.hoc.2012.04.002. Epub 2012 May 8.

Authors

Ayman Samkari¹, Eugene Hwang, Roger J Packer

Affiliation

¹ The Brain Tumor Institute, Division of Neurology, Children's National Medical Center, Washington, DC 20010, USA.

PMID: 22794288
DOI: 10.1016/j.hoc.2012.04.002

Abstract

This article presents an overview of medulloblastomas, central nervous system primitive neuroectodermal tumors, and germ cell tumors for the practicing oncologist. Discussion includes the definition of these tumors, histopathologic findings, molecular and genetic characteristics, prognoses, and evolution of treatment.

Publication types

Review

MeSH terms

Brain Neoplasms / diagnosis
Brain Neoplasms / therapy*
Humans
Medulloblastoma / diagnosis
Medulloblastoma / therapy*
Neoplasms, Germ Cell and Embryonal / diagnosis
Neoplasms, Germ Cell and Embryonal / therapy*
Neuroectodermal Tumors, Primitive / diagnosis
Neuroectodermal Tumors, Primitive / therapy*
Prognosis