Computer therapy compared with usual care for people with long-standing aphasia poststroke: a pilot randomized controlled trial

Stroke. 2012 Jul;43(7):1904-11. doi: 10.1161/STROKEAHA.112.650671.

Abstract

Background and purpose: The purpose of this study was to test the feasibility of conducting a randomized controlled trial to study the effectiveness of self-managed computer treatment for people with long-standing aphasia after stroke.

Method: In this pilot single-blinded, parallel-group, randomized controlled trial participants with aphasia were allocated to self-managed computer treatment with volunteer support or usual care (everyday language activity). The 5-month intervention period was followed by 3 months without intervention to investigate treatment maintenance.

Results: Thirty-four participants were recruited. Seventeen participants were allocated to each group. Thirteen participants from the usual care group and 15 from the computer treatment group were followed up at 5 months. An average of 4 hours 43 minutes speech and language therapy time and 4 hours volunteer support time enabled an average of 25 hours of independent practice. The difference in percentage change in naming ability from baseline at 5 months between groups was 19.8% (95% CI, 4.4-35.2; P=0.014) in favor of the treatment group. Participants with more severe aphasia showed little benefit. Results demonstrate early indications of cost-effectiveness of self-managed computer therapy.

Conclusions: This pilot trial indicates that self-managed computer therapy for aphasia is feasible and that it will be practical to recruit sufficient participants to conduct an appropriately powered clinical trial to investigate the effectiveness of self-managed computer therapy for people with long-standing aphasia. Clinical Trial Registration- www.controlled-trials.com. Unique identifier: ISRCTN91534629.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aphasia / economics
  • Aphasia / epidemiology*
  • Aphasia / therapy*
  • Cost-Benefit Analysis
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Self Care / economics
  • Self Care / methods*
  • Single-Blind Method
  • Stroke / economics
  • Stroke / epidemiology*
  • Stroke / therapy*
  • Therapy, Computer-Assisted / economics
  • Therapy, Computer-Assisted / methods*
  • Time Factors
  • Treatment Outcome

Associated data

  • ISRCTN/ISRCTN91534629