A high-throughput imaging system to quantitatively analyze the growth dynamics of plant seedlings

Integr Biol (Camb). 2012 Aug;4(8):945-52. doi: 10.1039/c2ib20020a. Epub 2012 Jun 12.

Abstract

Most current methods for analyzing the growth rate of plant seedlings are limited to low-throughput experimental configurations. We have developed an automatic system to investigate the dynamics of the growth of hypocotyls using Arabidopsis as model. This system is able to capture time-lapse infrared images of 24 seedlings automatically, with a spatial resolution of 2 μm per pixel and temporal interval of 5 min. Seedling length is rapidly calculated using automated geometric image-processing algorithms. With this high-throughput platform, we have investigated the genotype dependent difference of growth patterns, as well as the response to plant hormone - ethylene. Our analyses suggest that cytoskeleton function is not required in ethylene-induced hypocotyl inhibition. This novel integrative method can be applied to large-scale dynamic screening of plants, as well as any other image-based biological studies related to dynamic growth.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Arabidopsis / genetics*
  • Arabidopsis / physiology
  • Biotechnology / methods
  • Cytoskeleton / metabolism
  • Equipment Design
  • Ethylenes / chemistry
  • Genetic Techniques
  • Hypocotyl / genetics
  • Plant Growth Regulators / metabolism
  • Plant Physiological Phenomena
  • Seedlings / genetics*
  • Seedlings / metabolism*
  • Spectrophotometry, Infrared / methods
  • Time Factors

Substances

  • Ethylenes
  • Plant Growth Regulators
  • ethylene