2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels

MeSH terms

• 5-Methylcytosine / analogs & derivatives
• 5-Methylcytosine / blood
• Aged
• Aged, 80 and over
• Female
• Glutarates / blood*
• Humans
• Isocitrate Dehydrogenase / genetics*
• Leukemia, Myeloid, Acute / blood*
• Leukemia, Myeloid, Acute / diagnosis
• Leukemia, Myeloid, Acute / drug therapy
• Leukemia, Myeloid, Acute / genetics*
• Male
• Mutation*
• Neoplasm, Residual
• Prognosis
• Remission Induction
• Treatment Outcome