Antimicrobial therapy of febrile complications after high-dose chemotherapy and autologous hematopoietic stem cell transplantation--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Ann Hematol. 2012 Aug;91(8):1161-74. doi: 10.1007/s00277-012-1456-8. Epub 2012 May 26.

Abstract

More than 18,000 autolgous transplantation were performed in Europe in the year 2009. It as a routine procedure in experienced centres. Even if there is a low mortality rate, infections are a major issue after transplantation, occurring in more than 60 % of the patients. In this review we discuss all aspects of infections after autologous stem transplantation, including epidemiology, diagnostics, therapeutic algorithms, prophylaxis and supportive therapy.

Publication types

  • Evaluation Study
  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Communicable Diseases / drug therapy*
  • Communicable Diseases / epidemiology
  • Dose-Response Relationship, Drug
  • Fever / drug therapy*
  • Germany
  • Hematology / legislation & jurisprudence
  • Hematology / organization & administration
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Hematopoietic Stem Cell Transplantation / statistics & numerical data
  • Humans
  • Medical Oncology / legislation & jurisprudence
  • Medical Oncology / organization & administration
  • Occupational Medicine / legislation & jurisprudence
  • Occupational Medicine / organization & administration
  • Practice Guidelines as Topic*
  • Societies, Medical
  • Transplantation, Autologous / adverse effects
  • Transplantation, Autologous / statistics & numerical data

Substances

  • Anti-Infective Agents