Natural transmission of feline immunodeficiency virus from infected queen to kitten

Virol J. 2012 May 25:9:99. doi: 10.1186/1743-422X-9-99.

Abstract

Background: Feline immunodeficiency virus (FIV) is a naturally occurring lentivirus that infects cats. The primary mode of transmission occurs through bite wounds, and other routes are difficult to observe in nature.

Findings: The purpose of this study was to evaluate FIV transmission from queen to kitten in a colony of naturally infected stray cats. With this aim, a queen was monitored over a period of three years. A blood sample was taken to amplify and sequence gag, pol and env regions of the virus from the queen, two kittens and other cats from the colony.

Conclusion: Phylogenetic analysis showed evidence of queen to kitten transmission.

MeSH terms

  • Animals
  • Cats
  • Feline Acquired Immunodeficiency Syndrome / transmission*
  • Feline Acquired Immunodeficiency Syndrome / virology
  • Female
  • Immunodeficiency Virus, Feline / classification
  • Immunodeficiency Virus, Feline / genetics
  • Immunodeficiency Virus, Feline / isolation & purification
  • Immunodeficiency Virus, Feline / physiology*
  • Infectious Disease Transmission, Vertical / veterinary*
  • Male
  • Molecular Sequence Data
  • Pedigree
  • Phylogeny
  • Pregnancy
  • Retroviridae Proteins / genetics

Substances

  • Retroviridae Proteins

Associated data

  • GENBANK/EU375592
  • GENBANK/EU375593
  • GENBANK/EU375618
  • GENBANK/EU375619
  • GENBANK/EU375644
  • GENBANK/EU375645
  • GENBANK/JN836280
  • GENBANK/JN836281
  • GENBANK/JN836282
  • GENBANK/JN836283
  • GENBANK/JN836284
  • GENBANK/JN836285
  • GENBANK/JN836286
  • GENBANK/JN836287
  • GENBANK/JN836288
  • GENBANK/M25381