Diagnosis and surgical treatment of mucin-producing bile duct tumors

Hepatogastroenterology. 2012 Nov-Dec;59(120):2432-5. doi: 10.5754/hge12143.

Abstract

Background/aims: To summarize the experience of diagnosis and surgical treatment of mucin-producing bile duct tumors (MPBTs).

Methodology: A retrospective analysis was undertaken to determine the radiography characteristics and results of surgical treatment of MPBTs over the past 9 years. Only eight patients underwent such treatment. The detailed data of diagnosis, treatment and prognosis were carefully studied.

Results: Intermittent jaundice was the most frequently clinical manifestation of MPBTs, with unique characteristics on magnetic resonance cholangiopancreatography (MPCP) when compared with gallbladder carcino-ma, hilar cholangiocarcinoma and distal bile duct can-cer. All the 8 patients with MPBTs received appropriate surgical procedure and were cured.

Conclusions: Appropriate diagnosis and curative hepatectomy for MPBTs made it possible to achieve long-term survival.

MeSH terms

  • Aged
  • Bile Duct Neoplasms / chemistry
  • Bile Duct Neoplasms / mortality
  • Bile Duct Neoplasms / pathology
  • Bile Duct Neoplasms / surgery*
  • Bile Ducts, Extrahepatic / chemistry
  • Bile Ducts, Extrahepatic / pathology
  • Bile Ducts, Extrahepatic / surgery*
  • Bile Ducts, Intrahepatic / chemistry
  • Bile Ducts, Intrahepatic / pathology
  • Bile Ducts, Intrahepatic / surgery*
  • Biliary Tract Surgical Procedures* / adverse effects
  • Biliary Tract Surgical Procedures* / mortality
  • Biomarkers, Tumor / analysis*
  • Cholangiopancreatography, Magnetic Resonance
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mucins / analysis*
  • Postoperative Complications / surgery
  • Predictive Value of Tests
  • Reoperation
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome

Substances

  • Biomarkers, Tumor
  • Mucins