What changes in DNA methylation take place in individuals exposed to maternal smoking in utero?

Epigenomics. 2012 Apr;4(2):115-8. doi: 10.2217/epi.12.7.

Abstract

“It is becoming increasingly obvious that the period of time during fetal development is an important factor in the life-long health of the individual and such studies are essential to our ongoing deciphering of the molecular mechanisms underscoring the developmental origins of health and disease.”

Publication types

  • Editorial

MeSH terms

  • CpG Islands
  • Cytochrome P-450 CYP1A1 / genetics
  • Cytochrome P-450 CYP1A1 / metabolism
  • DNA Methylation*
  • Female
  • Humans
  • Maternal Exposure
  • Placenta / metabolism
  • Pregnancy
  • Promoter Regions, Genetic
  • Smoking*

Substances

  • Cytochrome P-450 CYP1A1