JETTA: junction and exon toolkits for transcriptome analysis

Bioinformatics. 2012 May 1;28(9):1274-5. doi: 10.1093/bioinformatics/bts134. Epub 2012 Mar 19.

Abstract

Summary: High-throughput genome-wide studies of alternatively spliced mRNA transcripts have become increasingly important in clinical research. Consequently, easy-to-use software tools are required to process data from these studies, for example, using exon and junction arrays. Here, we introduce JETTA, an integrated software package for the calculation of gene expression indices as well as the identification and visualization of alternative splicing events. We demonstrate the software using data of human liver and muscle samples hybridized on an exon-junction array.

Availability: JETTA and its demonstrations are freely available at http://igenomed.stanford.edu/~junhee/JETTA/index.html

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Alternative Splicing*
  • Exons
  • Gene Expression Profiling*
  • Genome-Wide Association Study*
  • Humans
  • Liver / metabolism
  • Muscles / metabolism
  • Oligonucleotide Array Sequence Analysis
  • RNA Splice Sites*
  • Software*

Substances

  • RNA Splice Sites