Analgesic effects of meloxicam administration on postoperative orthopedic pain in domestic pigeons (Columba livia)

Am J Vet Res. 2012 Mar;73(3):361-7. doi: 10.2460/ajvr.73.3.361.

Abstract

Objective: To assess the analgesic effects of 2 doses of meloxicam on the degree of postoperative orthopedic pain in pigeons.

Animals: 21 domestic pigeons (Columba livia).

Procedures: In each bird, a standardized osteotomy of 1 femur was performed and the fracture was immobilized with an intramedullary pin. Birds were randomly allocated to receive saline (0.9% NaCl) solution (control) or meloxicam (0.5 mg/kg [low dose] or 2.0 mg/kg [high dose]). The first treatment was administered i.m. after surgery was completed. Subsequent treatments were administered p.o. every 12 hours for 9 days. Degree of postoperative pain was assessed for the first 4 days after surgery by use of 3 methods: an electronic perch for assessment of weight-bearing load differential of the pelvic limbs, 4 pain scales, and analysis of video-recorded partial ethograms for bird activity and posture.

Results: No significant differences were observed between the control group and the low-dose meloxicam group in any tested variable. The high-dose meloxicam group had a greater degree of weight bearing on the affected limb from the second to the fourth postoperative day as well as lower pain scores for at least the first 2 postoperative days, compared with the other groups. Return to presurgical behavior was achieved faster in pigeons that received high-dose meloxicam than in the other groups. No adverse effects were observed.

Conclusions and clinical relevance: Administration of meloxicam at 0.5 mg/kg appeared ineffective in minimizing postoperative orthopedic pain in pigeons, but the 2.0 mg/kg dose provided quantifiable analgesia that appeared safe in this species in experimental conditions.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesia / veterinary
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Bird Diseases / drug therapy*
  • Bird Diseases / physiopathology
  • Bone Diseases / drug therapy
  • Bone Diseases / physiopathology
  • Bone Diseases / veterinary*
  • Columbidae*
  • Femoral Fractures / drug therapy
  • Femoral Fractures / physiopathology
  • Femoral Fractures / veterinary*
  • Male
  • Meloxicam
  • Motor Activity
  • Osteotomy / veterinary
  • Pain Measurement / veterinary
  • Pain, Postoperative / drug therapy
  • Pain, Postoperative / physiopathology
  • Pain, Postoperative / veterinary*
  • Thiazines / therapeutic use*
  • Thiazoles / therapeutic use*
  • Weight-Bearing

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Thiazines
  • Thiazoles
  • Meloxicam