Nosocomial outbreak of Klebsiella pneumoniae carbapenemase-producing Klebsiella oxytoca in Austria

Antimicrob Agents Chemother. 2012 Apr;56(4):2158-61. doi: 10.1128/AAC.05440-11. Epub 2012 Jan 30.

Abstract

To date, no outbreak of carbapenemase-producing bacteria has been reported for Austria. While outbreaks of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae have been increasingly reported, no outbreak caused by KPC-producing Klebsiella oxytoca has been described yet, to the best of our knowledge. We report an outbreak of KPC-producing K. oxytoca. In 5 months, 31 KPC-producing Klebsiella oxytoca strains were isolated from five patients. All patients were admitted to the same medical intensive care unit in Austria.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Austria / epidemiology
  • Bacterial Proteins / metabolism*
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Disease Outbreaks / statistics & numerical data*
  • Electrophoresis, Gel, Pulsed-Field
  • Female
  • Humans
  • Intensive Care Units
  • Klebsiella Infections / epidemiology*
  • Klebsiella Infections / microbiology
  • Klebsiella oxytoca / drug effects
  • Klebsiella oxytoca / enzymology*
  • Klebsiella oxytoca / genetics
  • Klebsiella pneumoniae*
  • Male
  • Microbial Sensitivity Tests
  • Polymerase Chain Reaction
  • Retrospective Studies
  • beta-Lactamases / metabolism*

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase