Cardiac screening prior to stimulant treatment of ADHD: a survey of US-based pediatricians

Pediatrics. 2012 Feb;129(2):222-30. doi: 10.1542/peds.2011-1574. Epub 2012 Jan 16.

Abstract

Objectives: To determine pediatricians' attitudes, barriers, and practices regarding cardiac screening before initiating treatment with stimulants for attention-deficit/hyperactivity disorder.

Methods: A survey of 1600 randomly selected, practicing US pediatricians with American Academy of Pediatrics membership was conducted. Multivariate models were created for 3 screening practices: (1) performing an in-depth cardiac history and physical (H & P) examination, (2) discussing potential stimulant-related cardiac risks, and (3) ordering an electrocardiogram (ECG).

Results: Of 817 respondents (51%), 525 (64%) met eligibility criteria. Regarding attitudes, pediatricians agreed that both the risk for sudden cardiac death (SCD) (24%) and legal liability (30%) were sufficiently high to warrant cardiac assessment; 75% agreed that physicians were responsible for informing families about SCD risk. When identifying cardiac disorders, few (18%) recognized performing an in-depth cardiac H & P as a barrier; in contrast, 71% recognized interpreting a pediatric ECG as a barrier. When asked about cardiac screening practices before initiating stimulant treatment for a recent patient, 93% completed a routine H & P, 48% completed an in-depth cardiac H & P, and 15% ordered an ECG. Almost half (46%) reported discussing stimulant-related cardiac risks. Multivariate modeling indicated that ≥1 of these screening practices were associated with physicians' attitudes about SCD risk, legal liability, their responsibility to inform about risk, their ability to perform an in-depth cardiac H & P, and family concerns about risk.

Conclusions: Variable pediatrician attitudes and cardiac screening practices reflect the limited evidence base and conflicting guidelines regarding cardiac screening. Barriers to identifying cardiac disorders influence practice.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Attention Deficit Disorder with Hyperactivity / diagnosis*
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Attention Deficit Disorder with Hyperactivity / mortality
  • Attitude of Health Personnel*
  • Cause of Death
  • Central Nervous System Stimulants / adverse effects*
  • Central Nervous System Stimulants / therapeutic use*
  • Child
  • Child, Preschool
  • Death, Sudden, Cardiac / etiology*
  • Electrocardiography / drug effects
  • Evidence-Based Medicine / statistics & numerical data
  • Female
  • Health Services Accessibility / statistics & numerical data*
  • Health Surveys
  • Humans
  • Liability, Legal
  • Male
  • Malpractice / legislation & jurisprudence*
  • Mass Screening / statistics & numerical data*
  • Middle Aged
  • Pediatrics / statistics & numerical data*
  • Practice Patterns, Physicians' / statistics & numerical data
  • Risk Assessment / statistics & numerical data
  • United States
  • Utilization Review

Substances

  • Central Nervous System Stimulants