Initial experience with polytetrafluoroethylene leaflet extensions for aortic valve repair

Eur J Cardiothorac Surg. 2012 Jun;41(6):1255-7; discussion 1258. doi: 10.1093/ejcts/ezr214. Epub 2012 Jan 12.

Abstract

Objectives: The purpose of this study is to evaluate our initial experience with aortic valve repair using polytetraflouroethylene (PTFE) leaflet extensions in congenital valvular disease.

Methods: From October 2008 through February 2011, 13 patients underwent aortic valvuloplasty by PTFE leaflet extensions. All valves were repaired in a tri-leaflet configuration using PTFE leaflet extensions. The median age at operation was 14 years (1.8-19.7 years) and the median weight was 58 kg (9.5-86 kg). Previous interventions included balloon valvuloplasty in two patients, aortic valvuloplasty in one and coarctation repair in one patient. Eight (73%) patients had combined aortic stenosis and insufficiency, three (23%) had isolated insufficiency and two (15%) had stenosis only. In 10 (77%) patients, a bicuspid aortic valve was present.

Results: The follow-up ranged from 2 to 30 months (mean follow-up 14.8 ± 9 months). At the latest echocardiography follow-up, six patients had none or trace aortic insufficiency, six patients had a mild aortic insufficiency and one patient had a mild-to-moderate insufficiency. The mean aortic insufficiency degree decreased from 1.8 ± 1.2 preoperatively to 0.8 ± 0.6 at the follow-up (P < 0.01). The mean gradient across the aortic valve decreased from 56 ± 40 mmHg preoperatively to 12 ± 13 mmHg at the follow-up (P < 0.0008). All patients are alive. There were no reoperations. The median hospital stay was 9 days (4-21 days).

Conclusions: The use of PTFE leaflet extensions is an effective technique for aortic valve reconstruction in congenital valvular disease. Long-term follow-up is necessary to assess the durability of this type of repair.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Aortic Valve / surgery*
  • Aortic Valve Insufficiency / congenital
  • Aortic Valve Insufficiency / surgery*
  • Aortic Valve Stenosis / congenital
  • Aortic Valve Stenosis / surgery*
  • Child
  • Child, Preschool
  • Follow-Up Studies
  • Humans
  • Infant
  • Polytetrafluoroethylene*
  • Prostheses and Implants*
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult

Substances

  • Polytetrafluoroethylene