Complex class 1 integron containing bla ( CTX-M-1 ) genes isolated from Escherichia coli: a potentially novel resistant gene-capturing tool kit

Curr Microbiol. 2012 Mar;64(3):265-70. doi: 10.1007/s00284-011-0062-7. Epub 2011 Dec 16.

Abstract

For this study, ten complex class 1 integron was characterized in Escherichia coli (E. coli) isolates from Zhenjiang. Among the ten isolates, five included the bla ( CTX-M-1 ) gene between orf513 and the IS 3000. Analysis the five isolates by PFGE showed that zj102 and zj562 had same patterns profiles, which suggested that the spread of a specific clone contributed to a wide dissemination of a particular type of integron; the results also indicated that the complex class 1 integron might be a potentially novel resistant gene-capturing tool kit.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cluster Analysis
  • Electrophoresis, Gel, Pulsed-Field
  • Escherichia coli / classification
  • Escherichia coli / enzymology*
  • Escherichia coli / genetics*
  • Evolution, Molecular
  • Humans
  • Integrons*
  • Molecular Epidemiology
  • Molecular Typing
  • beta-Lactamases / genetics*

Substances

  • beta-lactamase TEM-3
  • beta-Lactamases