Universal COI primers for DNA barcoding amphibians

Mol Ecol Resour. 2012 Mar;12(2):247-58. doi: 10.1111/j.1755-0998.2011.03090.x. Epub 2011 Dec 7.

Abstract

DNA barcoding is a proven tool for the rapid and unambiguous identification of species, which is essential for many activities including the vouchering tissue samples in the genome 10K initiative, genealogical reconstructions, forensics and biodiversity surveys, among many other applications. A large-scale effort is underway to barcode all amphibian species using the universally sequenced DNA region, a partial fragment of mitochondrial cytochrome oxidase subunit I COI. This fragment is desirable because it appears to be superior to 16S for barcoding, at least for some groups of salamanders. The barcoding of amphibians is essential in part because many species are now endangered. Unfortunately, existing primers for COI often fail to achieve this goal. Herein, we report two new pairs of primers (➀, ➁) that in combination serve to universally amplify and sequence all three orders of Chinese amphibians as represented by 36 genera. This taxonomic diversity, which includes caecilians, salamanders and frogs, suggests that the new primer pairs will universally amplify COI for the vast majority species of amphibians.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amphibian Proteins / genetics*
  • Amphibians / classification*
  • Amphibians / genetics
  • Animals
  • DNA Barcoding, Taxonomic / instrumentation
  • DNA Barcoding, Taxonomic / methods*
  • DNA Primers / genetics*
  • Electron Transport Complex IV / genetics*
  • Molecular Sequence Data
  • Phylogeny
  • Species Specificity

Substances

  • Amphibian Proteins
  • DNA Primers
  • Electron Transport Complex IV