Dual inhibition of Jak2 and STAT5 enhances killing of myeloproliferative neoplasia cells

Leukemia. 2012 Jun;26(6):1407-10. doi: 10.1038/leu.2011.338. Epub 2011 Dec 2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Dyskinesia Agents / pharmacology
  • Apoptosis*
  • Drug Synergism
  • Enzyme Inhibitors / pharmacology*
  • Humans
  • Janus Kinase 2 / antagonists & inhibitors*
  • Myeloproliferative Disorders / metabolism
  • Myeloproliferative Disorders / pathology*
  • Myeloproliferative Disorders / prevention & control*
  • Pimozide / pharmacology*
  • STAT5 Transcription Factor / antagonists & inhibitors*
  • Tumor Cells, Cultured

Substances

  • Anti-Dyskinesia Agents
  • Enzyme Inhibitors
  • STAT5 Transcription Factor
  • Pimozide
  • JAK2 protein, human
  • Janus Kinase 2