21-Hy-droxy-pregna-1,4-diene-3,20-dione

Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2122. doi: 10.1107/S1600536811028674. Epub 2011 Jul 23.

Abstract

The title compound, C(21)H(28)O(3), is a fungal transformed metabolite of decoxycorticosterone acetate, consisting of four fused rings A, B, C and D. Ring A is nearly planar, with a maximum deviation of 0.010 (3) Å from the least-squares plane, while the trans-fused rings B and C adopt chair conformations. The five-membered ring D is in an envelope conformation. The orientation of the side chain is stabilized by an intramolecular O-H⋯O hydrogen bond. In the crystal, adjecent mol-ecules are linked by C-H⋯O hydrogen bonds into extended zigzag chains along the a axis.