New insights into the pathogenesis of chronic myeloid leukaemia: towards a path to cure

Neth J Med. 2011 Oct;69(10):430-40.

Authors

N Thielen¹, G J Ossenkoppele, G-J Schuurhuis, J J W M Janssen

Affiliation

¹ Department of Haematology, VU University Medical Center, Amsterdam, the Netherlands. n.thielen@vumc.nl

PMID: 22058262

No abstract available

Publication types

Review

MeSH terms

Benzamides
Disease Progression
Fusion Proteins, bcr-abl / genetics
Fusion Proteins, bcr-abl / metabolism
Genes, abl*
Humans
Imatinib Mesylate
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / metabolism*
Piperazines / therapeutic use*
Protein Kinase Inhibitors / therapeutic use*
Protein-Tyrosine Kinases / genetics
Protein-Tyrosine Kinases / metabolism
Pyrimidines / therapeutic use*
Signal Transduction / genetics*

Substances

Benzamides
Piperazines
Protein Kinase Inhibitors
Pyrimidines
Imatinib Mesylate
Protein-Tyrosine Kinases
Fusion Proteins, bcr-abl