Choline-derivate-modified nanoparticles for brain-targeting gene delivery

Adv Mater. 2011 Oct 18;23(39):4516-20. doi: 10.1002/adma.201101899. Epub 2011 Sep 5.

Authors

Jianfeng Li¹, Lu Zhou, Deyong Ye, Shixian Huang, Kun Shao, Rongqin Huang, Liang Han, Yang Liu, Shuhuan Liu, Liya Ye, Jinning Lou, Chen Jiang

Affiliation

¹ Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA Department of Pharmaceutics, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China.

PMID: 21898606
DOI: 10.1002/adma.201101899

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Blood-Brain Barrier / metabolism
Boron Compounds / chemistry
Brain / metabolism*
Cell Line
Choline / chemistry*
Gene Transfer Techniques*
Male
Mice
Mice, Nude
Nanoparticles / chemistry*
Quaternary Ammonium Compounds / chemistry

Substances

4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
Boron Compounds
Quaternary Ammonium Compounds
Choline