SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts

Leukemia. 2012 Mar;26(3):542-5. doi: 10.1038/leu.2011.232. Epub 2011 Sep 2.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anemia, Refractory / genetics*
  • Anemia, Sideroblastic / genetics*
  • Base Sequence
  • Bone Marrow Cells / metabolism
  • Female
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Lymphocytes / metabolism
  • Male
  • Middle Aged
  • Mutation Rate
  • Mutation*
  • Phosphoproteins / genetics*
  • RNA Splicing Factors
  • Ribonucleoprotein, U2 Small Nuclear / genetics*

Substances

  • Phosphoproteins
  • RNA Splicing Factors
  • Ribonucleoprotein, U2 Small Nuclear
  • SF3B1 protein, human