The role of cytokines and chemokines in Histoplasma capsulatum infection

Cytokine. 2012 Apr;58(1):112-7. doi: 10.1016/j.cyto.2011.07.430. Epub 2011 Aug 26.

Abstract

Histoplasma capsulatum is a prevalent fungal pathogen in the United States, infecting approximately 500,000 individuals each year. Host protection requires an intact cell-mediated immune response. In this review, we will discuss how cytokines and chemokines influence protective immunity in H. capsulatum infection.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Chemokines / immunology*
  • Cytokines / immunology*
  • Histoplasma / immunology*
  • Histoplasmosis / immunology*
  • Humans
  • Mice
  • Receptors, CCR5 / biosynthesis
  • Th1 Cells / immunology
  • Th17 Cells / immunology

Substances

  • Chemokines
  • Cytokines
  • Receptors, CCR5