CUL4B: trash talking at chromatin

Erin M Green; Or Gozani

doi:10.1016/j.molcel.2011.07.015

CUL4B: trash talking at chromatin

Mol Cell. 2011 Aug 5;43(3):321-3. doi: 10.1016/j.molcel.2011.07.015.

Authors

Erin M Green¹, Or Gozani

Affiliation

¹ Department of Biology, Stanford University, Stanford, CA, USA.

Abstract

In this issue, Nakagawa and Xiong (2011) reveal a mechanism targeting WDR5 for proteolysis dependent on the X-linked mental retardation gene, CUL4B. This provides a link between the stability of a chromatin factor and gene expression implicated in neurological pathogenesis.

Publication types

Comment

Abstract

Publication types

Grants and funding