Dynamic 'Spot Sign' Resolution following INR Correction in a Patient with Warfarin-Associated Intracerebral Hemorrhage

Case Rep Neurol. 2011 May;3(2):154-9. doi: 10.1159/000330304. Epub 2011 Jul 13.

Abstract

Hematoma expansion in intracerebral hemorrhage is associated with poor clinical outcome. The 'spot sign' is a radiological marker that is associated with hematoma expansion, and thought to represent active extravasation of contrast. This case demonstrates the use of dynamic CT angiography in identifying the time-dependent appearance of a spot sign in a patient with warfarin-associated intracerebral hemorrhage. Repeat imaging is also presented which verified cessation of the spot sign after INR correction.

Keywords: CT angiography; Intracerebral hemorrhage; Spot sign.

Publication types

  • Case Reports