Making whole genome multiple alignments usable for biologists

Bioinformatics. 2011 Sep 1;27(17):2426-8. doi: 10.1093/bioinformatics/btr398. Epub 2011 Jul 19.

Abstract

Summary: Here we describe a set of tools implemented within the Galaxy platform designed to make analysis of multiple genome alignments truly accessible for biologists. These tools are available through both a web-based graphical user interface and a command-line interface.

Availability and implementation: This open-source toolset was implemented in Python and has been integrated into the online data analysis platform Galaxy (public web access: http://usegalaxy.org; download: http://getgalaxy.org). Additional help is available as a live supplement from http://usegalaxy.org/u/dan/p/maf.

Contact: james.taylor@emory.edu; anton@bx.psu.edu

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Genomics / methods*
  • Humans
  • Internet
  • Sequence Alignment / methods*
  • Sequence Analysis, DNA*
  • Software*
  • User-Computer Interface