Antibiotic prophylaxis for cesarean delivery: survey of maternal-fetal medicine physicians in the U.S

J Matern Fetal Neonatal Med. 2012 Aug;25(8):1264-6. doi: 10.3109/14767058.2011.605485. Epub 2012 May 3.

Abstract

Objective: To describe practices concerning antibiotic prophylaxis for cesarean delivery among maternal-fetal medicine (MFM) physicians in the United States.

Methods: A 10-item self-administered survey about their routine use of antibiotics for cesarean delivery was mailed once only to a random sample of 1000 US-based fellows of the Society of Maternal-Fetal Medicine in November 2009.

Results: There were a total of 250 respondents from 40 US states between 10/09 and 4/2010, corresponding to a response rate of 25%. Among respondents, 95.5% reported routine use of a cephalosporin only (including 84.4% who reported use of cefazolin) as antibiotic prophylaxis for cesarean delivery; less than 3% reported use of an extended spectrum regimen such as cefazolin + azithromycin. Preoperative administration of antibiotic prophylaxis was reported by 84.6% compared to 15.0% who reported giving antibiotic prophylaxis after umbilical cord clamping. Administration of a single dose of antibiotic was reported by 96%.

Conclusion: The majority of MFM specialists in the US report routine and preoperative use of a single prophylactic dose of a 1st generation cephalosporin for cesarean delivery.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibiotic Prophylaxis / statistics & numerical data*
  • Azithromycin / administration & dosage
  • Azithromycin / therapeutic use
  • Cefazolin / administration & dosage
  • Cefazolin / therapeutic use
  • Cesarean Section / rehabilitation
  • Cesarean Section / statistics & numerical data*
  • Delivery, Obstetric / statistics & numerical data
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Maternal-Child Health Centers
  • Obstetrics / methods
  • Obstetrics / statistics & numerical data
  • Physicians* / statistics & numerical data
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Pregnancy
  • Surgical Wound Infection / epidemiology
  • Surgical Wound Infection / prevention & control*
  • United States / epidemiology
  • Workforce

Substances

  • Azithromycin
  • Cefazolin