A complex karyotype masked a cryptic variant t(8;21)(q22;q22) in a child with acute myeloid leukemia

Leuk Lymphoma. 2011 Aug;52(8):1593-6. doi: 10.3109/10428194.2011.576286. Epub 2011 Jun 10.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Child
  • Chromosome Banding
  • Chromosomes, Human, Pair 21 / genetics*
  • Chromosomes, Human, Pair 8 / genetics*
  • Core Binding Factor Alpha 2 Subunit / genetics
  • Genetic Variation
  • Humans
  • Karyotyping
  • Leukemia, Myeloid / diagnosis
  • Leukemia, Myeloid / drug therapy
  • Leukemia, Myeloid / genetics*
  • Male
  • Oncogene Proteins, Fusion / genetics
  • RUNX1 Translocation Partner 1 Protein
  • Reverse Transcriptase Polymerase Chain Reaction
  • Translocation, Genetic*

Substances

  • AML1-ETO fusion protein, human
  • Core Binding Factor Alpha 2 Subunit
  • Oncogene Proteins, Fusion
  • RUNX1 Translocation Partner 1 Protein