Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

Rebecca Shepherd; Simon A Forbes; David Beare; S Bamford; Charlotte G Cole; Sari Ward; Nidhi Bindal; Prasad Gunasekaran; Mingming Jia; Chai Yin Kok; Kenric Leung; Andrew Menzies; Adam P Butler; Jon W Teague; Peter J Campbell; Michael R Stratton; P Andrew Futreal

doi:10.1093/database/bar018

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

Database (Oxford). 2011 May 23:2011:bar018. doi: 10.1093/database/bar018. Print 2011.

Authors

Rebecca Shepherd¹, Simon A Forbes, David Beare, S Bamford, Charlotte G Cole, Sari Ward, Nidhi Bindal, Prasad Gunasekaran, Mingming Jia, Chai Yin Kok, Kenric Leung, Andrew Menzies, Adam P Butler, Jon W Teague, Peter J Campbell, Michael R Stratton, P Andrew Futreal

Affiliation

¹ Cancer Genome Project, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.

Abstract

Catalogue of Somatic Mutations in Cancer (COSMIC) (http://www.sanger.ac.uk/cosmic) is a publicly available resource providing information on somatic mutations implicated in human cancer. Release v51 (January 2011) includes data from just over 19,000 genes, 161,787 coding mutations and 5573 gene fusions, described in more than 577,000 tumour samples. COSMICMart (COSMIC BioMart) provides a flexible way to mine these data and combine somatic mutations with other biological relevant data sets. This article describes the data available in COSMIC along with examples of how to successfully mine and integrate data sets using COSMICMart. DATABASE URL: http://www.sanger.ac.uk/genetics/CGP/cosmic/biomart/martview/.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Data Mining*
Databases, Genetic*
Humans
Mutation / genetics*
Neoplasms / genetics*
Search Engine

Abstract

Publication types

MeSH terms

Grants and funding