Biological risk of older adults with visual impairments

J Nutr Health Aging. 2011 Apr;15(4):296-302. doi: 10.1007/s12603-010-0296-2.

Abstract

Objectives: To investigate whether biological markers of health differ among older adults with visual impairment compared to those with normal vision.

Design: We use data from the National Health and Nutrition Examination Survey (1999 - 2006) to investigate clinically defined at-risk levels for 10 biological markers.

Setting: Survey participants were non-institutionalized.

Participants: Nationally representative (U.S.) sample of older adults age 65 and older, categorized as having blindness (20/200 or worse), low vision (20/40 to 20/100) or normal vision (better than 20/40).

Intervention: Separate binary logistic regressions (one for each biomarker, with two at-risk cut points for BMI: obese and underweight) were computed to determine the odds of having at-risk levels of each biomarker.

Measurements: Biomarkers included: systolic and diastolic blood pressure, high-density lipoprotein, low-density lipoprotein (LDL) cholesterol, total cholesterol, glycated hemoglobin, body mass index (BMI), fasting triglycerides, C-reactive protein, and plasma homocysteine.

Results: Older adults who were blind were more likely to have high-risk levels of LDL cholesterol, homocysteine, and to be underweight (BMI>18.5). Similarly, older adults with LV were more likely to have high-risk levels of homocysteine compared to older adults with normal vision.

Conclusion: As several of the high-risk biomarkers associated with visual impairment were diet-related, our results suggest the importance of nutrition and diet programs aimed towards educating older people who are visually impaired.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Biomarkers / analysis*
  • Blindness / blood
  • Blindness / epidemiology
  • Blindness / etiology
  • Blood Pressure / physiology
  • Body Mass Index
  • C-Reactive Protein / metabolism
  • Diet*
  • Female
  • Health Surveys*
  • Homocysteine / blood
  • Humans
  • Lipid Metabolism / physiology
  • Logistic Models
  • Male
  • Risk Factors
  • Vision Disorders / blood
  • Vision Disorders / epidemiology*
  • Vision Disorders / etiology
  • Vision, Low / blood
  • Vision, Low / epidemiology
  • Vision, Low / etiology

Substances

  • Biomarkers
  • Homocysteine
  • C-Reactive Protein