Objective: To evaluate the effects of pulse high volume hemofiltration (PHVHF) in the treatment of multiple organ dysfunction syndrome (MODS).
Methods: Twenty-five patients with MODS received treatment with PHVHF.
Results: The 25 patients showed significantly decreased BUN, Scr, and K(+) levels after the treatment (P<0.01), and PaO(2)/FiO(2) was improved in almost all the patients (P<0.05). The APACHEII scores were significantly improved (P<0.05) in these patients and 18 of them were cured and discharged. PHVHF therapy was associated with a survival rate of 72%.
Conclusions: PHVHF can be effective for treatment of MODS.