Continued emergence and changing epidemiology of oseltamivir-resistant influenza A(H1N1)2009 virus, United Kingdom, winter 2010/11

Euro Surveill. 2011 Feb 3;16(5):19784.

Abstract

During the winter period 2010/11 27 epidemiologically unlinked, confirmed cases of oseltamivir-resistant influenza A(H1N1)2009 virus infection have been detected in multiple, geographically dispersed settings. Three of these cases were in community settings, with no known exposure to oseltamivir. This suggests possible onward transmission of resistant strains and could be an indication of a possibility of changing epidemiology of oseltamivir-resistant influenza A(H1N1)2009 virus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antiviral Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Drug Resistance, Viral*
  • Female
  • Humans
  • Infant
  • Influenza A Virus, H1N1 Subtype / drug effects*
  • Influenza A Virus, H1N1 Subtype / genetics
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza, Human / drug therapy
  • Influenza, Human / epidemiology*
  • Influenza, Human / transmission
  • Influenza, Human / virology
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Neuraminidase / genetics
  • Oseltamivir / therapeutic use*
  • Pandemics
  • Polymorphism, Single Nucleotide
  • Population Surveillance
  • Seasons
  • United Kingdom / epidemiology
  • Young Adult

Substances

  • Antiviral Agents
  • Oseltamivir
  • Neuraminidase