Cell migration: GSK3β steers the cytoskeleton's tip

Gozde Yucel; Anthony E Oro

doi:10.1016/j.cell.2011.01.023

Cell migration: GSK3β steers the cytoskeleton's tip

Cell. 2011 Feb 4;144(3):319-21. doi: 10.1016/j.cell.2011.01.023.

Authors

Gozde Yucel¹, Anthony E Oro

Affiliation

¹ Program in Epithelial Biology, Stanford University, School of Medicine, CA 94305, USA.

Abstract

Directed cell migration polarizes the cytoskeleton, allowing the cell to move toward migratory cues. In this issue, Wu et al. (2011) demonstrate that the glycogen synthase kinase 3β (GSK3β) controls microtubule architecture and polarized movement of skin stem cells during wound healing in mammals by regulating the microtubule crosslinking protein ACF7.

Publication types

Comment

Grants and funding

R01 AR052785/AR/NIAMS NIH HHS/United States