Experience of the Reina Sofia hospital in lobar lung transplantation

Transplant Proc. 2010 Oct;42(8):3214-6. doi: 10.1016/j.transproceed.2010.05.048.

Abstract

The number of patients awaiting lung transplantation has steadily increased over the past decade, but the number of donors has remained relatively stable. Owing to the increasing scarcity of donor lungs, especially for pediatric and small adult recipients, advanced operative strategies for the use of larger grafts for smaller recipients have been developed. Size matching between donors and recipients represents one of the organ distribution criteria widely accepted by lung transplantation teams. However, in some cases it is not possible to allocate a donor to the corresponding size-compatible recipient. To avoid possible complications derived from the implantation of oversized lungs into smaller recipients, various methods of downsizing are applied for cadaveric donor lungs, such as lobar transplantation. We review our experience in 6 patients undergoing volume reduction of the lung graft by lobar resection at the time of transplantation. Graft volume reduction by anatomic resection (lobar transplantation) is a reliable and safe procedure to overcome size disparities between the donor and the recipient of a lung transplant, and thus to maximize the number of donors.

Publication types

  • Review

MeSH terms

  • Adult
  • Female
  • Hospitals*
  • Humans
  • Lung Transplantation*
  • Male
  • Middle Aged
  • Spain
  • Tissue Donors