Prevalence, treatment and control of dyslipidaemia in Switzerland: still a long way to go

Eur J Cardiovasc Prev Rehabil. 2010 Dec;17(6):682-7. doi: 10.1097/HJR.0b013e32833a09ab.

Abstract

Background: There is little information regarding the prevalence and management of dyslipidaemia in Switzerland.

Design: Cross-sectional population-based study of 3238 women and 2846 men aged 35-75.

Methods: Dyslipidaemia prevalence, treatment and control were defined according to PROCAM guidelines adapted to Switzerland.

Results: About 29% of the overall sample presented with dyslipidaemia, of which 39% were treated and 58% of those treated were controlled. Among the 710 patients with personal history of cardiovascular disease (CVD) and/or diabetes, 632 (89%) presented with dyslipidaemia, of which 278 (44%) and 134 (21%) patients were treated and adequately controlled, respectively. On multivariate analysis, hypolipidaemic drug treatment was positively related with age and body mass index (P for trend <0.001), and negatively related with smoking status (P for trend <0.002), whereas personal history of CVD and/or diabetes had no effect [odds ratio (OR)=1.12, 95% confidence interval (CI): 0.90-1.38]. Adequate control of lipid levels was negatively related with female sex (OR=0.65, 95% CI: 0.45-0.94) and personal history of CVD and/or diabetes (OR=0.42, 95% CI: 0.30-0.59). When personal history of CVD and/or diabetes was replaced by PROCAM risk categories, patients in the highest risk were also less well controlled.

Conclusion: In this population-based study, one-third of the participants was dyslipidaemic, but less than half was treated and only one-fifth was adequately controlled. The low treatment and control levels among individuals at high risk for CVD calls for a better application of recommendations regarding personal preventive measures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cardiovascular Diseases / epidemiology
  • Chi-Square Distribution
  • Cross-Sectional Studies
  • Diabetes Mellitus / epidemiology
  • Dyslipidemias / drug therapy*
  • Dyslipidemias / epidemiology*
  • Dyslipidemias / prevention & control
  • Female
  • Guideline Adherence
  • Humans
  • Hypolipidemic Agents / therapeutic use*
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Practice Guidelines as Topic
  • Prevalence
  • Risk Assessment
  • Risk Factors
  • Switzerland / epidemiology
  • Time Factors
  • Treatment Outcome

Substances

  • Hypolipidemic Agents