ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis

Vet J. 2011 Sep;189(3):356-8. doi: 10.1016/j.tvjl.2010.06.021. Epub 2010 Jul 27.

Abstract

The ermB gene was identified in 111 erythromycin resistant isolates of Streptococcus uberis from cases of bovine mastitis associated either with a constitutive (47/111) or an inducible (64/111) phenotype, as well as a phenotypic resistance to all macrolides tested. Resistance to lincosamides was identified in 14 other isolates of S. uberis from bovine mastitis cases and was mainly mediated by the linB gene; resistance conferred by a combination of two genes (linB-lnuD, ermB-linB) was also detected.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Cattle
  • Drug Resistance, Bacterial / genetics*
  • Erythromycin / pharmacology*
  • Female
  • France
  • Genes, Bacterial*
  • Genotype
  • Lincosamides / pharmacology
  • Macrolides / pharmacology
  • Mastitis, Bovine / microbiology
  • Microbial Sensitivity Tests
  • Phenotype
  • Pristinamycin / pharmacology
  • Streptococcus / drug effects*
  • Streptococcus / genetics*
  • Streptococcus / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Lincosamides
  • Macrolides
  • Pristinamycin
  • Erythromycin