The Microbiology of Community-acquired Peritonitis in Children

Pediatr Infect Dis J. 2011 Feb;30(2):131-5. doi: 10.1097/INF.0b013e3181eed7a4.

Abstract

Background: microbiologic data are lacking regarding pediatric community-acquired peritonitis (CAP).

Methods: we conducted a 2-year retrospective single center study. Consecutive children undergoing CAP surgery were included. Microbiology and antimicrobial susceptibility of peritoneal isolates were analyzed.

Results: a total of 70 children from 3 months to 14 years of age were included. A total of 123 bacterial isolates were analyzed. Escherichia coli was the predominant aerobic organism (51% of isolates); 54.8% were susceptible to amoxicillin whereas 90.3% were susceptible to amoxicillin-clavulanate. Anaerobes accounted for 29% of isolates, and 94.3% of strains were susceptible to amoxicillin-clavulanate and 68.5% were susceptible to clindamycin. Pseudomonas aeruginosa was present in 6% of isolates and in 10% of children. The presence of E. coli resistant to amoxicillin or to amoxicillin-clavulanate was the only independent risk factor associated with postoperative peritonitis.

Conclusion: microbiology of pediatric CAP is similar to adult CAP with a predominancy of E. coli and anaerobes. P. aeruginosa in peritoneal samples had no apparent influence on the outcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / pharmacology
  • Bacteria / classification
  • Bacteria / drug effects
  • Bacteria / isolation & purification*
  • Child
  • Child, Preschool
  • Community-Acquired Infections / epidemiology*
  • Community-Acquired Infections / microbiology*
  • Female
  • Humans
  • Infant
  • Male
  • Microbial Sensitivity Tests
  • Peritonitis / epidemiology*
  • Peritonitis / microbiology*
  • Prevalence
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents