[Late gadolinium enhancement in the diagnostics of ischemic heart disease: technical principles, contrast optimization and clinical application]

Radiologe. 2010 Jun;50(6):523-31. doi: 10.1007/s00117-010-1986-9.
[Article in German]

Abstract

Background: The purpose of the study was to explore a "dark blood" technique and to compare it with a standard inversion recovery gradient echo (IR GRE) sequence in the visualization of myocardial infarction.

Patients and methods: A total of 9 patients were examined with standard IR GRE and a "dark blood" sequence 15 mins after contrast medium application (0.2 mmol/kg body weight gadobenate dimeglumine). Contrast-to-noise ratios (CNR) were calculated for each sequence.

Results: The CNR(inf-lvc) was significantly higher in the "dark blood" technique compared to the IR GRE sequence, while the CNR(inf-myo) was significantly lower.

Conclusions: Small subendocardial infarctions may be easier to detect with the "dark blood" technique. However, the standard IR GRE sequence is superior in the demarcation of infarctions in relation to the myocardium and cannot be replaced by the "dark blood" technique.

Publication types

  • English Abstract

MeSH terms

  • Contrast Media / administration & dosage
  • Female
  • Humans
  • Image Enhancement / methods*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Meglumine / administration & dosage
  • Meglumine / analogs & derivatives*
  • Middle Aged
  • Myocardial Ischemia / diagnosis*
  • Organometallic Compounds / administration & dosage*
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Contrast Media
  • Organometallic Compounds
  • gadobenic acid
  • Meglumine