Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms

Leukemia. 2010 May;24(5):1094-6. doi: 10.1038/leu.2010.52. Epub 2010 Apr 8.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Base Sequence
  • DNA-Binding Proteins / genetics
  • Dioxygenases
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Janus Kinase 2 / genetics
  • Middle Aged
  • Molecular Sequence Data
  • Mutation / genetics*
  • Myelodysplastic Syndromes / genetics*
  • Myelodysplastic Syndromes / pathology
  • Myeloproliferative Disorders / genetics*
  • Myeloproliferative Disorders / pathology
  • Proto-Oncogene Proteins / genetics

Substances

  • DNA-Binding Proteins
  • Proto-Oncogene Proteins
  • IDH2 protein, human
  • Isocitrate Dehydrogenase
  • IDH1 protein, human
  • Dioxygenases
  • TET2 protein, human
  • JAK2 protein, human
  • Janus Kinase 2