Primary diffuse large B-cell central nervous system lymphoma presenting as an acute space-occupying subdural mass

J Neurosurg. 2010 Aug;113(2):384-7. doi: 10.3171/2010.2.JNS091554.

Abstract

Primary dural lymphomas are very rare tumors--usually low-grade B-cell lymphomas of mucosa-associated lymphoid tissue type or marginal zone B-cell lymphomas. Primary dural involvement by diffuse large B-cell lymphoma is extremely rare, with only a few cases reported in the literature. The authors present an unusual case of primary dural involvement by a high-grade diffuse large B-cell lymphoma that presented as an acute subdural space-occupying mass and required emergency neurosurgical intervention.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Antimetabolites, Antineoplastic / administration & dosage
  • Biopsy
  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / surgery
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Dura Mater / diagnostic imaging*
  • Dura Mater / pathology
  • Dura Mater / surgery
  • Fatal Outcome
  • Female
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / diagnostic imaging*
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / surgery
  • Methotrexate / administration & dosage
  • Middle Aged
  • Reoperation
  • Subdural Space / diagnostic imaging*
  • Subdural Space / pathology
  • Subdural Space / surgery
  • Tomography, X-Ray Computed*

Substances

  • Antimetabolites, Antineoplastic
  • Methotrexate