The incidence of multiple pregnancy after in vitro fertilization and embryo transfer, gamete, or zygote intrafallopian transfer

N Bollen; M Camus; C Staessen; H Tournaye; P Devroey; A C Van Steirteghem

doi:10.1016/s0015-0282(16)54122-3

The incidence of multiple pregnancy after in vitro fertilization and embryo transfer, gamete, or zygote intrafallopian transfer

Fertil Steril. 1991 Feb;55(2):314-8. doi: 10.1016/s0015-0282(16)54122-3.

Authors

N Bollen¹, M Camus, C Staessen, H Tournaye, P Devroey, A C Van Steirteghem

Affiliation

¹ Center for Reproductive Medicine, Vrije Universiteit Brussel, Belgium.

PMID: 1991529
DOI: 10.1016/s0015-0282(16)54122-3

Abstract

This retrospective study concerns the incidence of multiple pregnancy after the replacement of three conceptus using different techniques of assisted reproduction. During a 2-year period, 713 in vitro fertilization-embryo transfers (IVF-ETs) with three embryos, 190 gamete intrafallopian transfers (GIFT) with three oocytes, and 161 zygote intrafallopian transfers (ZIFT) with three zygotes were performed. Although we observed significant differences in implantation and pregnancy rates (PRs), the three techniques resulted in high multiple PR. At 20 weeks, 16% of GIFT pregnancies, 27% of ZIFT pregnancies, and 32% of IVF-ET pregnancies were multiple. Therefore we recommend to limit the number of conceptus transferred to a maximum of three in all cases.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Embryo Transfer*
Female
Fertilization in Vitro*
Gamete Intrafallopian Transfer*
Humans
Male
Pregnancy
Pregnancy, Multiple*
Reproductive Techniques*
Retrospective Studies